Endocrine Abstracts

Discovery of novel peptides leads to the elucidation of unknown regulatory systems in the body and to the clinical development of diagnosis and therapeutics for diseases. We have used peptidomics approach to profile a complete set of secretory peptides from cultured human endocrine cells and identified two novel carboxy-terminally amidated peptides, 25-amino acid neuroendocrine regulatory peptide (NERP)-1 and 38-amino acid NERP-2, derived from a neurosecretory protein VGF (JBC...